Who We Are


Why Manchester? – The Northern Powerhouse

In 2015 David Cameron proposed that the North would be the stage for Britain’s economic and technical renaissance. Ideally located in the North West, and Britain’s second largest city, Manchester is at the heart of this revolution in innovation, infrastructure, research, and manufacturing. In August 2016, PM Theresa May echoed Cameron’s desire to reinvigorate the North as a centre of excellence, pledging to “help the great cities and towns of the North pool their strengths and take on the world”.

We are located at Manchester Science Park, an innovation hub with tight links to the University of Manchester. We are a stones throw away from the National Graphene Institute, and within easy reach of bio-technology hubs such as Alderly Park and Daresbury. Furthermore the university has world leading life sciences and material sciences departments, and the Sir Henry Royce Institute for Advanced Materials will be on our doorstep.

Invented, developed, designed, and built in Manchester, we are proud of the companies routes. From February 2017 we are offering free imaging to universities across the country, starting with those in the Greater Manchester area. We want those who are on the forefronts of imaging in both the life and materials sciences to test the limits of our revolutionary microscope, opening up new frontiers in the nanoscopic world.


Microsphere technology has long been hailed as the holy grail of optical microscopy. A spherical piece of glass that could increase the resolution of an optical microscope to that of super-resolution. However, no one has managed to take this disruptive and revolutionary idea and make it a reality. Until now.

In 2011, at the University of Manchester Professor Lin Li and Dr. Wei Guo developed a method that has paved the way for the application of microsphere technology in microscopy. Dr Guo was at the time a student of Professor Lin, and their work together and subsequent breakthrough was covered by the BBC, the NY Times, and the journal Nature. Six years later and their discovery has grown into a microscopy start-up looking to disrupt the world of super-resolution microscopy.

We are a Manchester based start up that has broken the theoretical limit of what we can see with light. Our patented technology- SMAL – redefines the limits of optical microscopy. Our first product, the NANOPSIS M has been designed and developed in the city’s science park. We have harnessed the power of non-contact microsphere technology – breaking the world record for the smallest object that the eye can see. Our technique was invented and developed by Professor Lin Li with the help of Dr Wei Guo. Their shared expertise in laser manufacturing and optics allowed them to pioneer the technology that drives the NANOPSIS M, the world’s most powerful wide-field optical microscope.


Our staff is diverse, bringing together industry experts form multiple fields including, meta-material fabrication, laser manufacturing, microscopy, and computer imaging. Our varied backgrounds make nanopsis ideally placed to take on the challenges of the competitive and ever-changing bio-tech market.

We are launching the NANOPSIS M in Manchester this June.


Meet the team.

Professor Lin Li

Professor Lin Li invented SMON (submerged microsphere optical nanoscope) in 2013. He holds a chair of laser engineering, and is the Director of the Laser Processing Research Centre at The University of Manchester. He received Wolfson Research Merit Award from the Royal Society for his research on laser nano-fabrication and nano-imaging, and received the Researcher of the Year medal in Engineering and Physical Sciences at The University of Manchester in 2014. Lin co-founded LIG-Technologies in 2014 and serves as Chairman of LIG Technologies Group.

Dr. Wei Guo

Wei Guo (Director) is one of the inventors of the microsphere optical nanoscope and has successfully managed a technology company (Advanced Laser Technology). He holds the position of Experimental Officer in the School of Mechanical, Aerospace & Civil Engineering, University of Manchester….